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San Francisco Giants vs. Seattle Mariners odds, picks and best bets

Geoff Clark
USA Today Sportsbookwire

TheSan Francisco Giants(23-24) will host theSeattle Mariners(22-26) Wednesday at Oracle Park in what will be considered a Mariners home game. MLB changed the venue to San Francisco due to unhealthy air conditions caused by wildfires near Seattle.

This is the first game of the two-game series and the first pitch is scheduled for 9:45 p.m. ET. Below, we analyze the Giants-Mariners MLB betting odds and lines, with picks and best bets.

Giants vs. Mariners: Projected starting pitchers

LHPDrew Smylyvs. RHPLjay Newsome

Smyly: 0-0 with a 2.92 ERA, 1.14 WHIP, 13.9 K/9 and 3.6 BB in 12/1 IP over 4 games, including 2 starts.

  • Last start: No-decision with 4 IP, 3 H, 2 ER, 7 K and 2 BB in a 7-3 win vs. the Texas Rangers Aug. 1.

Newsome: 0-0 with a 3.24 ERA, 0.96 WHIP, 7.6 K/9 and 0 BB in 8 1/3 IP over 3 games, including 2 starts.

  • This is the 23-year-old's rookie season. Newsome's last start was a 1 1/3-inning, no-decision in which he was forced to exit the game after taking a line drive off his right wrist Sept. 8.

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Giants vs. Mariners: Key injuries

(Get the latest injury news here.)

Giants

  • CAramis Garcia(hip) out

Mariners

  • OFMitch Haniger(back) out
  • CTom Murphy(foot) out
  • 2BSam Haggerty(forearm) out
  • SS J.P. Crawford (bereavement) out

Also see:BaseballHQ Fantasy Baseball

Giants vs. Mariners: Odds, lines, picks and betting tips

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 3:05 p.m. ET.

Prediction

Giants 9, Mariners 2

Money line (ML)

The unfortunate conditions of the wildfires in Washington causing Giants-Mariners to be moved to San Francisco gives theGIANTS (-150)an edge. They lost their previous three games (all on the road) following a five-game win streak (all in San Francisco).

The Mariners (+135) have a 10-17 record on the road in 2020 and it's difficult to imagine where the organization's head is at given the circumstances. The baseball side of things has looked good recently for Seattle as it has won three of the previous four games.

Seattle is starting a rookie coming off an injury against a sneaky good San Francisco lineup that ranks in the top 10 of several hitting categories. Plus, the Mariners' bullpen has the third-worst ERA.

It's a lot ofchalkbutGIANTS (-150)should be easy money.

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Run line/Against the spread (ATS)

TheGIANTS -1.5 (+105)have the fifth-best home run line record in the majors but the Mariners +1.5 (-125) have a winning RL record as a road team. For obvious reasons, this is a tough spot for Seattle but I don'tloveSan Francisco's value here. I'd stillTAKE GIANTS -1.5because their lineup hits so well at home.

Over/Under (O/U)

The combined Over/Under record of Giants-Mariners is 52-35-8 O/U. San Francisco's home games go Over the total at the second-highest rate and Seattle's road games also go Over at the second-highest rate.

Seventy percent of games the Giants are favored in go Over the total and 64% of games Mariners are dogs go Over the total.OVER 9 (-110)is the play.

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